Fascinating video shows heart cells that builds a heart: ScienceCealert

Scientists have caught the complicated dance of heart cells to build a heart in a fascinating new period that was caused during the development of a mouse embryo.

The pictures were taken using a technology called Light Sheet Microscopy (LSM). Essentially, LSM includes scanning a sample with a thin light leaf, which creates sharp, detailed, three -dimensional images of living tissue without damaging it.

Researchers from the University College London (UCL) and the Francis Crick Institute in Great Britain used the method to pursue how mouse embryo cells specialize in roles, divide and to organize the structure of a heart.

The team marked the different types of cells with fluorescent markers and then recorded every two minutes for up to 41 hours. The resulting time -lapse shows a greeting group of inconspicuous cells that come together to make a living and to defeat Mausherz in a way that is really captivating.

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It's not just beautiful; It helped the team to uncover new details about heart development. Surprisingly, individual cells already seemed to know where they have to go and what roles they will play in the end, also four or five hours after the first embryonic cell.

“Our results show that the determination of the heart fate and the directional cell movement in the embryo can be regulated much earlier than current models suspect,” says Kenzo Ivanovitch, development biologist at the UCL.

“This changes our understanding of heart development fundamentally by showing that a chaotic cell migration is actually determined by hidden patterns that ensure proper heart formation.”

Although this is far from practical advantages, a better understanding of this process could possibly lead to new treatment options for congenital heart defects, the team said.

Research was published in The Embo Journal.