The management of several heart risks cuts early death in high blood pressure

In a recently carried out study, it was examined how eight different risk factors for heart disease significantly reduced the likelihood of premature death in people with high blood pressure. It shows the need for a broad approach to prevent or treat high blood pressure.

As the main cause of early deaths, high blood pressure or high blood pressure is well researched. In most studies, however, it is examined how dealing with a single risk factor – for example a balanced diet – affects the condition.

Now new research, US Chinese collaboration, has examined how the management of several cardiovascular risk factors at the same time influences things such as cholesterol, smoking and weight and high blood pressure.

“Our study provides mandatory evidence that effective joint management of health risks can neutralize the increased mortality risks that are typically connected to high blood pressure,” said Professor LU Qi, MD, PHD, the corresponding author and director of the obstacle research center of the study at the School of Public Health and Tropical Medicine at Tulane University.

Qi was connected by other researchers from New Orleans' Tulane University, Harvard Th Chan School of Public Health and the second Xiangya Hospital of Central South University, China. They received data from the British Bio Chancement over 70,898 adults with high blood pressure and 224,069 Consistent participants without high blood pressure, for whom cancer or heart disease had not been diagnosed at the beginning of their studies. All participants were followed on average 13 and a half years.

Their common risk factor control was assessed based on eight modifiable cardiovascular risk factors: blood pressure, body mass index (BMI), waist size, cholesterol level with low dense lipoprotein (LDL), glycated hemoglobin (HBA1c), urine peak levels (albuminuria), Smoking and physical activity. COX proportional Hazards models were used to examine the relationship between the control of different factors and early death. Simply expressed, the COX model compares “danger rates” (the risk or the likelihood of an event) between different groups taking into account the course of time. It enables an estimate of how much the individual factor increases or reduces the danger rate without assuming the form of danger (i.e. whether the risk is constant and, in contrast to other statistical models, increases or decreases over time).

The researchers found that participants who had checked more risk factors had a significantly lower risk of early death. In hypertensive participants with “optimal risk factors”, they had checked at least seven of the eight risk factors, the premature death reduced by 40%, cancer -related early death by 39%, premature cardiovascular death by 53%and premature deaths by “other causes”. However, they found that participants who managed to control this number of risk factors in the minority; Only 7.3% did this. Above all, however, the researchers found that hypertensive participants who had at least four controlling risk factors had no higher risk of early death than participants without high blood pressure.

They said their results underline the need for a broad approach to treat or prevent high blood pressure, which would require a shift from concentration to one or two changeable risk factors.

“The [study] increases the need for more extensive clinical strategies that go beyond blood pressure control, ”said Qi.

Research was published in the journal Precision clinic medicine.

Source: Chinese Academy of Sciences about Newswise