The study emphasizes facts about anaphylaxis, which is induced by goat and sheep's milk

Two thirds of people with a history of cow milk allergy, which were restored from the milk allergy of their cow at the time of the event of the event of the goat and sheep's milk laxie become.¹

This new research on the milk allergy by goats and sheep was written by a team of investigators such as Guillaume Pouessel from the Department of Pediatrics of the Children's Hospital in Roubaix, France. Pouessel et al. Highlets that an isolated allergy to goat and sheep's milk, if it is not connected to cow milk allergy, is considered rare.²

Nevertheless, the investigators found that there have been several cases that described earlier examinations of isolated anaphylaxis in connection with goat and sheep milk.

“We wanted to characterize [goat and sheep’s milk] Anaphylaxis cases recorded by the Allergy-Wald Network (AVN), a French-speaking network that mainly collects data from France, compare the main features and time trends of anaphylaxis by by [goat and sheep’s milk] with those of other foods, including [cow’s milk] And peanut, ”wrote Pouessel and colleagues.¹

The co -authors found the number of cases of anaphylaxis, which were induced by the AVN between 2002 and 2024 a total of 3,285 cases. Among these it was shown that 97 cases (3.0%) were written to goat and sheep milk. Under this sub -group of cases it was emphasized that 58.8% occurred in men, and there was an average age between 10.5 years (interquartile area: 5.3–17.0).

75.3% of dairy-induced anaphylaxis events of the goat and sheep were shown by Pouessel and colleagues under the age of 19. In the course of its study period, the team did not provide statistically significant climbs in cases of goat and sheep milklaxy (sheep's milk -hanaphylaxisP = .16). They added that 57.7% of the subjects had a well-known allergy to goat and sheep milk in their analysis before their anaphylactic event.

A prehistory of the allergy to cow's milk was determined by the investigation team in 13.4% of goat and sheep's milk -anaphylaxis cases. Under these cases it was shown that 3 subjects are still allergic to cow's milk at the time of the event, and a single topic was subjected to oral immunotherapy.

The team emphasized that 34.0% of the subjects had the anaphylaxis of grade 3 and 4.1% reactions of 4 degrees 4, including 2 fatal results. Test participants with the dairy reactions of goat and cow were generally older (average age 10.5 years compared to 1.5 years; P <10⁻³) and more often a history of asthma (44.5% compared to 17.4%; P <10⁻³) compared to those with anaphylaxis that is triggered by cow's milk.

Goat and sheep milk -hanaphylaxis cases also took older people compared to peanut-anaphylaxis. Conversely, compared to anaphylaxis as a result of other foods, the milk -related cases of goats and sheep were younger people (average age 10.5 compared to 19.0 years; P <10⁻³).

Such cases were also more often associated with asthma (44.5% compared to 26.1%; P <10⁻³), bronchospasm (25.3% compared to 36.1%; P = 0.002) and a higher severity of the reactions – grade 3 (29.7% compared to 4%) and degrees 4 (4.1% compared to 1.0%) ()P = .007). They also had a well -known allergy to trigger food (57.7% compared to 33.1%; P <10⁻³)

Goat and sheep milk allergy made 3% of all food-induced anaphylaxis cases in the investigators' data record and showed a stable rate over time. This number is in contrast to the rate of 0.9%registered in the European anaphylaxis tab, which may indicate a difference that results from regional nutritional preferences.

The milk and sheep, Pouessel and Coauthors are increasingly integrated into a number of different products, including food supplements, formulas for infants, personal care products and pharmaceuticals. As a result, such an increase can contribute to a future increase in anaphylaxis cases in relation to its use.

Overall, the results indicate that anaphylaxis in relation to the milk of goats and sheep can represent a clear clinical profile in contrast to other food extermamation – characterized by its severity (including the two deaths mentioned above), a tendency, later childhood and a remarkable connection to the comorbid asthma.

“Clinic should be aware of the special features of [goat’s and sheep’s milk] Anaphylaxy, the risk of [goat’s and sheep’s milk] Allergy in patients with [cow’s milk] Allergy also after recovery, ”they wrote.¹ “Data about [goat’s and sheep’s milk] Allergy from other countries may have to introduce the inclusion of [goat’s and sheep’s milk] In the list of 14 mandatory allergens to explain food. “

References

1. Pouessel G., Vaia es, Chatain C, et al. (2025). Anaphylaxis induced by goat and sheep's milk: an allergen that we should have monitored. Allergy. https://doi.org/10.1111/all.16581.

2. O Benjamin-van Aalst, C Dupont, L van der Zee et al. “Goat milk allergy and a potential role for goat milk in cow milk allergy”, nutrients 16, No. 15 (2024): 2402.