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Brain health score identified as an important predictor of the risk of stroke in women

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Women with a higher McCance brain care value (BCS)-a score, the physical, lifestyle and social-emotional factors measure a lower risk of experiencing a stroke or another cerebrovascular event, which reduces the blood circulation of the brain, according to a new study that was carried out by experts from the General Brigham. The results are published in neurology.

“Our results underline that the McCance Brain Care Score is a valuable instrument for predicting cerebrovascular event risk in women that remains a main cause of the stroke for stroke,” said the senior author Nirupama Yechoor, MD, MSC, the Minister of Neurology of the Massachusett General Hospital (MGH).

“Our study also underlines the need for a broader, long -term research in various population groups and examines how changes in the values ​​affect the risk of stroke and the associated events.”

One of five women between the ages of 55 and 75 in the United States is expected to experience a stroke. Earlier studies have shown that the McCance brain care score can predict the risk of stroke, dementia and depression in the general population. In the BCS, 12 modifiable risk factors range from 0 to 21 points, including physical components (blood pressure, blood sugar, cholesterol and body mass index [BMI]), Lifestyle factors (alcohol consumption, nutrition, smoking, physical activity and sleep) and social-emotional factors (social relationships, stress and sense of meaning in life).

Together with the leading author Devanshi Choksi, MBBS, MPH, a research scholarship in the Department of Neurology in MGH, Yechoor, and colleagues from 21,271 women with a middle age of 57.9 years of 57.9. Using data collected by the WHS, the investigators calculated the BCS of women and follow-up data used to compare ratings and cerebrovascular occurrence incidence.

They found that a higher score with a reduced risk of cerebrovascular events correlated during the lifespan. With an average of 22.4 years, 6.1% of the participants had a cerebrovascular event (stroke or temporary ischemic attack). Those with a five-point higher baseline BC (the mean base value of 15) was a cerebrovic event after adapting age, menopausal status, the use of hormonal replacement therapy and other risk factors for cardiovascular diseases with 37%.

Further information:
Devanshi Choksi et al. neurology (2025). DOI: 10.1212/WNL.00000000213674

Provided by Mass General Brigham

Quote: Brain health score, which was identified as an important predictor of the risk of stroke in women (2025, May 19), from May 19, 2025

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